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报告结外非霍奇金淋巴瘤218例。原发于鼻咽48例,鼻腔23例,扁桃体32例,口腔10例,胃肠道54例,骨19例,软组织7例,皮肤7例,其他部位18例。除6例(2.8%)滤泡型外,均为弥漫型212例(97.2%)。按国际工作分类,以大细胞性(包括免疫母细胞性)和混合细胞性为多占132例(60.5%)。发生部位最常见为胃肠道54例(24.8%),其次为鼻咽部48例(22%),第三位为扁桃体32例(14.7%);若将发生于上呼吸道和上消化退病例合计共113例(51.8%)。居本组病例首位,胃肠道发生者居第二位。全部病例石蜡切片用单克隆抗体LCA、L26、UCHL1和Mac387作免疫组化染色,证实为B细胞性淋巴瘤146例(72.6%),T细胞性淋巴瘤51例(25.4%),4例(2%)未能分类,无一例为组织细胞性。在胃肠道(46例)和扁桃体(27例)以B细胞性为主(92%和90%),鼻腔淋巴瘤大多为T细胞性15例(68%)。鼻咽淋巴瘤则B细胞性24例(57%)较T细胞性18例(43%)稍多。骨的淋巴瘤19例中B细胞性占15例(79%),其中10例原发于颌骨属Burkitt淋巴瘤。
Reported 218 cases of extranodal non-Hodgkin’s lymphoma. There were 48 cases of nasopharyngeal origin, 23 cases of nasal cavity, 32 cases of tonsils, 10 cases of oral cavity, 54 cases of gastrointestinal tract, 19 cases of bone, 7 cases of soft tissue, 7 cases of skin, and 18 cases of other parts. Except for 6 (2.8%) follicular types, they were all diffuse types (97.2%). According to the international work classification, 132 cases (60.5%) were mostly large cells (including immunoblastic) and mixed cells. The most common site was gastrointestinal tract in 54 cases (24.8%), followed by nasopharynx in 48 cases (22%), and the third in the tonsils in 32 cases (14.7%); if it occurred in the upper respiratory tract and A total of 113 cases (51.8%) of the upper ablation cases were included. The patients in this group had the highest number of cases, and those who developed gastrointestinal tract ranked second. In all cases, paraffin sections were stained with monoclonal antibodies LCA, L26, UCHL1, and Mac387 for immunohistochemical staining. 146 cases (72.6%) of B-cell lymphomas and 51 cases of T-cell lymphomas (25.4%) were confirmed. 4 cases (2%) failed to be classified, and none were histiocytic. In the gastrointestinal tract (46 cases) and the tonsils (27 cases) were mainly B cells (92% and 90%), and nasal lymphomas were mostly T cells in 15 cases (68%). In nasopharyngeal lymphoma, B cells were found in 24 cases (57%) compared with T cells in 18 cases (43%). Of the 19 cases of bone lymphoma, 15 (79%) were B cells, of which 10 were primary Burkitt lymphomas of the jaw.