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目的观察放射治疗对骨转移瘤的止痛效果。方法采用 10MV-X线或 60CO-γ线对 156例经 X线摄片、 ECT、 CT或 MRI确诊的骨转移瘤疼痛患者进行放射治疗。结果放疗后患者疼痛完全缓解率为 51.9%,总缓解率为 98.1%。高剂量短疗程放疗同低剂量长疗程的止痛效果无显著差异 (P >0.05),单发性与多发性转移的疗效相似 (P >0.05),放疗对不同原发病灶的骨转移同样有效。结论放射治疗是治疗骨转移疼痛的有效方法,不同剂量分割方法的止痛效果相似。
Objective To observe the analgesic effect of radiation therapy on bone metastases. Methods Radiotherapy was performed on 156 patients with bone metastases who were diagnosed with X-ray, ECT, CT, or MRI using 10MV-X or 60CO-γ line. Results After the radiotherapy, the complete remission rate was 51.9%, and the total remission rate was 98.1%. There was no significant difference in the analgesic effect between high-dose, short-course radiotherapy and low-dose, long-course therapy (P > 0.05). The efficacy of single and multiple metastases was similar (P > 0.05). Radiotherapy was equally effective for bone metastasis of different primary lesions. Conclusion Radiotherapy is an effective method for the treatment of bone metastasis pain. Different dose splitting methods have similar analgesic effects.