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目的:探讨前哨淋巴结活检术在乳腺癌治疗中的意义。方法:选取48例乳腺癌患者,分为实验组与对照组,对照组予以常规手术治疗,实验组则予以保乳前哨淋巴结活检术治疗,比较两组乳腺癌患者的美容效果、生活质量、手术时间、术中出血量、拔管时间、引流总量、并发症发生率、局部复发及转移情况。结果:实验组美容效果及生活质量问卷评分均显著优于对照组;实验组手术时间、术中出血量、拔管时间、引流总量以及并发症发生率均显著优于对照组(P<0.05);实验组患者复发率与转移率均为4.17%,对照组复发率为4.17%,转移率为8.33%,两组比较差异无统计学意义(P>005)。结论:前哨淋巴结活检术在乳腺癌治疗中不仅具有较好的美容效果,还可降低并发症发生率、缩短手术与拔管时间、减少术中出血量和引流总量,提高生活质量,且复发率及转移率与传统手术无明显差异。
Objective: To investigate the significance of sentinel lymph node biopsy in the treatment of breast cancer. Methods: Forty eight patients with breast cancer were selected and divided into experimental group and control group. The control group was given conventional surgery. The experimental group was treated with breast-conserving sentinel lymph node biopsy. The cosmetic effect, quality of life, Time, intraoperative blood loss, extubation time, the total drainage, the incidence of complications, local recurrence and metastasis. Results: The scores of cosmetic effect and quality of life questionnaire in experimental group were significantly better than those in control group. The operation time, intraoperative blood loss, extubation time, total drainage volume and complication rate in experimental group were significantly better than those in control group (P <0.05 ). The recurrence rate and metastasis rate were 4.17% in the experimental group, 4.17% in the control group and 8.33% in the control group. There was no significant difference between the two groups (P> 005). CONCLUSIONS: Sentinel lymph node biopsy not only has good cosmetic effect in the treatment of breast cancer, but also can reduce the incidence of complications, shorten the operation and extubation time, reduce the amount of intraoperative bleeding and drainage, improve quality of life, and recurrence Rate and transfer rate and no significant difference between traditional surgery.