玻璃体内注射曲安奈德治疗视网膜中央静脉阻塞引起的黄斑水肿

来源 :世界核心医学期刊文摘.眼科学分册 | 被引量 : 0次 | 上传用户:menes127
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Purpose: To evaluate treatment of macular oedema due to central retinal vein o cclusion (CRVO) with intravitreal triamcinolone acetonide. Methods: In a prospec tive case series, 13 patients with macular oedema due to non-ischaemic CRVO rec eived an intravitreal injection of 4 mg triamcinolone acetonide. Examination inc luded assessment of best corrected visual acuity (BCVA) for distance and reading , measurement of intraocular pressure (IOP), fluorescein angiography and high re solution imaging by optical coherence tomography, preoperatively and 1 week, 1 m onth, 3, 6 and 9 months postoperatively. Results: Preoperative mean BCVA was 0.9 ±0.4 for distance vision and 1.0±0.3 for reading acuity, respectively. A signi ficant improvement in distance VA (0.5±0.3, p< 0.001) and reading acuity (0.7± 0.3, p=0.03) was observed until 3 months and 6 months, respectively. Mean macula r thickness was significantly reduced until 9 months postoperatively. Conclusion : Intravitreal injection of triamcinolone acetonide led to a significant improve ment in mean VA in patients with macular oedema due to CRVO. However, the signif icant effect was not permanent and persisted for a maximum of 6 months. Purpose: To evaluate treatment of macular edema due to central retinal vein o cclusion (CRVO) with intravitreal triamcinolone acetonide. Methods: In a prospec tive case series, 13 patients with macular oedema due to non-ischaemic CRVO recived an intravitreal injection of 4 mg / mL triamcinolone acetonide. Examination inc luded assessment of best corrected visual acuity (BCVA) for distance and reading, measurement of intraocular pressure (IOP), fluorescein angiography and high re solution imaging by optical coherence tomography, preoperatively and 1 week, 3, 6 and 9 months postoperatively. Results: Preoperative mean BCVA was 0.9 ± 0.4 for distance vision and 1.0 ± 0.3 for reading acuity, respectively. A signi ficant improvement in distance VA (0.5 ± 0.3, p <0.001) and reading acuity ( 0.7 ± 0.3, p = 0.03) was observed until 3 months and 6 months, respectively. Mean macula r thickness was significantly reduced until 9 months postoperatively. Conclusion: Intravitreal injection of tri amcinolone acetonide led to a significant improve ment in mean VA in patients with macular odedema due to CRVO. However, the signif icant effect was not permanent and persisted for a maximum of 6 months.
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