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研究眩晕的药物治疗方法几乎全是对症疗法。治疗眩晕有三个主要目的:一是消除运动幻觉,应用具有前庭抑制剂性质的药物,主要是抗胆碱和抗组胺药;二是降低伴有植物神经的和精神的症状(头晕、呕吐、焦虑),抗多巴胺能药即用于此目的;三是增强受损伤的前庭代偿过程,以使大脑建立一种新的感觉平衡。其他用于眩晕治疗的药物有苯并二氮车类,组胺类药,拟交感药和钙拮抗剂,但作用机理了解甚少。由于方法学的局限,以临床试用的数据评价抗眩晕药物常常是不可靠的。这就解释了为何处方特点主要以经验为根据,以及各国之间存在的显著差异。从目前对于前庭系统受体亚型和神经调节体的关注,可以期望会出现新的疗法。人们必须准备以可靠的临床方法来评价这些潜在的新治疗药物。
Medical treatment of vertigo is almost entirely symptomatic treatment. The treatment of vertigo has three main purposes: one is to eliminate motor hallucinations, the application of drugs with the properties of vestibular inhibition, mainly anticholinergic and antihistamines; the second is to reduce the symptoms associated with autonomic and mental (dizziness, vomiting, Anxiety), anti-dopaminergic that is used for this purpose; third is to enhance the damaged vestibular compensatory process, so that the brain to establish a new sense of balance. Other drugs used to treat vertigo include benzodiazepines, histamines, sympathomimetics and calcium antagonists, but little is known about the mechanism of action. Due to the limitations of methodology, it is often unreliable to evaluate anti-dizziness drugs based on clinical trial data. This explains why prescribing characteristics are largely based on experience and the significant differences between countries. From the current focus on the vestibular system receptor subtypes and neuromodulators, new treatments may be expected. People must be prepared to evaluate these potential new therapies in a reliable clinical way.