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目的探讨重症肺炎患儿血小板计数变化及其与预后的关系。方法收集崇州市人民医院儿科住院治疗的重症肺炎患儿50例,根据患儿的预后分为两组:好转组32例和恶化组18例。分别在入院后第l、2、3、4、5 d进行血小板计数监测,分析血小板计数与预后的关系。结果好转组和恶化组患儿入院第1 d的血小板计数之间比较,差异无统计学意义(P>0.05),好转组入院后第2、3 d的血小板计数显著下降,之后维持稳定状态;而恶化组患儿从入院后第2 d起,血小板计数呈持续下降趋势,两组间比较差异有统计学意义(P<0.05)。结论动态监测血小板的变化对判断重症肺炎患儿预后具有重要的预警价值,可作为评估患儿预后的一个比较可靠的监测指标。
Objective To investigate the changes of platelet count in children with severe pneumonia and its relationship with prognosis. Methods Fifty children with severe pneumonia admitted to Pediatric Hospital of Chongzhou People’s Hospital were divided into two groups according to their prognosis: 32 cases of remission group and 18 cases of deterioration group. Platelet count was monitored on the first, second, third, fourth and fifth days after admission, and the relationship between platelet count and prognosis was analyzed. Results There was no significant difference in the platelet counts on the first day after admission (P> 0.05) between the improved group and the deteriorated group. The platelet count of the improved group decreased significantly on the 2nd and 3rd day after admission, and remained stable afterwards. In the worsening group, the platelet count showed a continuous decreasing trend from the 2nd day after admission, with significant difference between the two groups (P <0.05). Conclusion The dynamic monitoring of platelet changes in judging the prognosis of children with severe pneumonia has an important early warning value, can be used as a prognostic indicator of a more reliable monitoring.