1 病历摘要我院1998年8月发生1例口服头孢氨苄过敏休克病例,经抢救而愈。一般表现为药热、皮疹、血清病样反应。皮疹的发生可以有很大的不同,在大多数情况下反应是温和的、自制的,然而,有生命危险的反应如Stevens—Johnson综合征、青性表皮坏死和脱落性皮炎也会偶然出现。2 讨论头孢菌素过敏反应的发生率为青霉素1/4-1/10。其过敏反应的发生机制较为复杂,目前认为头 1 medical records in our hospital in August 1998 occurred in 1 case of oral cephalexin shock cases, the more the rescue. The general performance of drug fever, rash, serum disease-like response. Rash can occur quite differently, and in most cases the reaction is mild and self-made. However, life-threatening reactions such as Stevens-Johnson syndrome, epidermal necrosis and exfoliative dermatitis also occur by chance. 2 Discussion The incidence of cephalosporin allergy penicillin 1 / 4-1 / 10. The mechanism of its allergic reaction is more complicated, the current head