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目的:探讨经脐单孔腹腔镜手术治疗卵巢输卵管巨大囊肿的可行性和安全性。方法:回顾性分析2018年1月至2019年6月上海交通大学医学院附属瑞金医院收治的38例卵巢输卵管巨大囊肿患者,分为单孔腹腔镜组(18例)和传统腹腔镜组(20例),比较两组患者手术时间、术中出血量、镇痛例数等围手术期相关指标。结果:38例患者均顺利完成手术,无中转开腹,单孔腹腔镜组无增加辅助孔;术后均未发生并发症,无囊液外漏。单孔腹腔镜组18例患者脐孔部位瘢痕隐藏满意。单孔腹腔镜组和传统腹腔镜组手术时间[(51.67±13.72)min vs (55.50±14.59)min]、术中出血量[(52.22±24.38)ml vs (61.50±28.88)ml]、术后首次肛门排气时间[(25.77±8.59)h vs (27.60±6.67)h]差异均无统计学意义(均n P>0.05);单孔腹腔镜组需术后镇痛例数(2例vs 12例)少于传统腹腔镜手术组(n P<0.05);下床活动时间[(20.95±3.65)h vs (26.95±5.43)h]及术后出院时间[(3.11±0.68)h vs (4.30±1.21)h]短于传统腹腔镜手术组(均n P0.05); The number of cases requiring postoperative analgesia in the single-port laparoscopy group (2 cases vs 12 cases) was less than that in the traditional laparoscopy group (n P<0.05); The out of bed activity time [(20.95±3.65)h vs (26.95±5.43)h] and postoperative discharge time [(3.11±0.68)h vs (4.30±1.21)h] were shorter than those in the traditional laparoscopy group (alln P<0.05). All 38 patients were followed up in the gynecological clinic for 6-24 months. The incision healed well without recurrence.n Conclusions:Transumbilical single-port laparoscopic surgery for giant ovarian and fallopian tube cysts is reliable and safe when the possibility of malignant ovarian and fallopian tube tumors was excluded before operation.