论文部分内容阅读
目的:探讨Inoue法经皮球囊二尖瓣成形术(PBMV)的效果和安全性。方法:分析我院自1992年至今资料相对完整的1625例PBMV患者,评价手术前后心导管、超声心动图与临床心功能等各项指标,并统计手术成功率与并发症发生率。结果:技术性成功率98.71%。左房平均压术前(22.76±8.85)mmHg(1mmHg=0.133kPa),术后(14.15±6.11)mmHg(P<0.001);左房内径术前(49.42±9.71)mm,术后(45.16±8.27)mm(P<0.001);二尖瓣瓣口面积术前(1.11±0.29)cm2,术后(2.01±0.65)cm2(P<0.001);跨二尖瓣平均压差术前(12.18±5.85)mmHg,术后(3.21±3.77)mmHg(P<0.001)。手术并发症例数96例(5.90%),二尖瓣反流71例(4.37%),心脏穿孔或心包填塞13例(0.80%),系统性栓塞9例(0.55%),其他5例(0.31%)。导致死亡2例(0.12%),需要急诊外科干预11例(0.68%)。结论:PBMV治疗二尖瓣狭窄是一种安全、有效的方法。
Objective: To investigate the efficacy and safety of Inoue percutaneous balloon mitral valvuloplasty (PBMV). Methods: The data of 1625 PBMV patients with relatively complete data in our hospital from 1992 to now were analyzed. The indexes of cardiac catheterization, echocardiography and clinical cardiac function before and after surgery were evaluated. The success rate of surgery and complication rate were calculated. Results: The technical success rate was 98.71%. The mean left atrial pressure was (22.76 ± 8.85) mmHg (1mmHg = 0.133kPa) and 14.15 ± 6.11 mmHg after operation (P <0.001) 8.27 mm (P <0.001); mitral valve area preoperatively (1.11 ± 0.29) cm2 and postoperative (2.01 ± 0.65) cm2 (P <0.001) 5.85) mmHg, postoperative (3.21 ± 3.77) mmHg (P <0.001). There were 96 cases (5.90%) with surgical complications, 71 cases (4.37%) with mitral regurgitation, 13 cases (0.80%) with cardiac perforation or pericardiocentesis, 9 cases (0.55%) with systemic embolism and 5 %). Two cases resulted in death (0.12%), requiring emergency surgical intervention in 11 cases (0.68%). Conclusion: PBMV is a safe and effective method for the treatment of mitral stenosis.