目前为数不多的抗流感病毒药物都有其不足之处。例如金刚胺(Amantadine)和金刚乙胺(Rimantadine)仅能预防和治疗甲型流感病毒的感染,而三氮唑核苷(Ribavirin,下简称RV)及干扰素仅是喷雾或滴鼻给药时才对甲型和乙型流感有效且均有毒性。流感病毒有甲,乙,丙三型,它们的临床症状相似,最好能找到对三型流感均有活性的药物。流感病毒的繁殖的几个步骤可利用作为寻找抗病毒药物的靶(见表1)。其中有些是病毒 At present, one of the few anti-influenza virus drugs has its shortcomings. For example, Amantadine and Rimantadine can only prevent and treat the infection of the Influenza A virus, whereas ribavirin (hereinafter referred to as RV) and interferon are only administered by spraying or nasal drops It is effective and both toxic to influenza A and B viruses. Influenza virus A, B, C type three, their clinical symptoms are similar, it is best to find the three type of influenza are active drugs. Several steps in the breeding of influenza virus are available as targets for finding antiviral drugs (see Table 1). Some of these are viruses