论文部分内容阅读
人类微小病毒(HPV)可引起各种临床综合征,以传染性红斑最常见,也可使慢性溶血性贫血患者发生再障危象。孕妇染感可危及胎儿。作者所在地区发生传染性红斑流行期间,有6例孕妇血清学检查证实HPV感染,其中4例足月分娩正常婴儿,另2例在中孕期引产娩出显著水肿伴贫血胎儿。这2例流产的胎儿镜下有类似的组织病理学特征:显示一种幼白-幼红细胞反应,肝细胞炎性浸润且有过多铁色素沉着。造血细胞核内有嗜酸性小体形成。胎盘和胎儿组织的匀浆和提取物用~(32)P标记的HPV-DNA探针作密码杂交分析,发现胎盘和胎儿的多种脏器均有HPV-DNA,提示他们在宫腔内已受感染。作者认为,在感染宿主中,HPV对快速分裂细胞(尤其是幼红
Human parvovirus (HPV) can cause a variety of clinical syndromes, with the most common infectious erythema, chronic hemolytic anemia can also occur in patients with aplastic anemia crisis. Pregnant women can endanger the fetus. During the epidemic of infectious erythema in the area where the author was located, serological tests of 6 pregnant women confirmed HPV infection, of which 4 had full-term delivery of normal infants and the other 2 had significant edema with anemia in the second trimester. These 2 aborted fetuses had similar histopathological features: a young white-erythroid reaction, inflammatory infiltrates of the liver cells with excessive iron pigmentation. Hematopoietic nuclei have eosinophils formed. Homogenates and Extracts from Placenta and Fetal Tissues Human papillomavirus (HPV) -DNA was detected using ~ (32) P-labeled HPV-DNA probes for codon assignment analysis, suggesting that they are present in the uterine cavity infected. The authors suggest that HPV is responsible for rapidly dividing cells (especially macules) in infected hosts