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目的了解儿童中毒型细菌性痢疾（简称毒痢）的病原学特点，探讨毒痢脑型的诊断及治疗。方法对我院１９９７年收治的儿童毒痢进行临床分型及资料分析，复习有关文献。结果５２例毒痢中脑型３３例，休克型３例，混合型１６例。有脑水肿表现者（包括脑型及混合型）４９例，占总数的９４２％。均以发热、惊厥、腹泻发病，惊厥在发热后１～２３小时出现，腹泻在发热后１～１７小时出现。便培养阳性率４４９％，均为福氏２ａ型。结论对福氏２ａ型痢疾杆菌的流行趋势和耐药应继续监测；对毒痢脑水肿的抢救必须分秒必争，早期诊断及治疗是降低病死率、改善预后的关键
Objective To understand the etiological characteristics of children’s poisoning bacillary dysentery (referred to as poison dysentery), explore the diagnosis and treatment of poison dysentery brain. Methods Clinical typing and data analysis of children’s poisoned diarrhea admitted in our hospital in 1997, review the relevant literature. Results 52 cases of poison dysentery in 33 cases of cerebral, shock in 3 cases, mixed 16 cases. There are 49 cases of brain edema (including cerebral and mixed type), accounting for 94 2% of the total. All with fever, convulsions, diarrhea, onset, convulsions 1 to 23 hours after fever, diarrhea in 1 to 17 hours after fever. Then the positive rate of culture 44 9%, are Fu-2a type. Conclusions The epidemic trend and drug resistance of Shigella flexneri type 2a dysentery should be monitored continuously. The rescue of DHI hydrocephalus must be time-warped. Early diagnosis and treatment are the keys to reduce mortality and improve prognosis