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目的评价不同穿刺方式在前列腺癌诊断中的临床价值。方法回顾分析475例患者施行前列腺穿刺的临床资料。经直肠穿刺组(A组)110例,经会阴12针穿刺组(B组)144例,经会阴24针穿刺组(C组)221例,对比三组在各前列腺特异性抗原(PSA)水平上的阳性率及并发症的发生率等指标,并进一步分析C组患者阳性针数的分布情况。结果 PSA<10.0μg/L的患者中,C组的阳性率(34.2%)明显高于A组(10.8%)和B组(13.0%);PSA10.0～60.0μg/L和PSA>60.0μg/L的患者中,三组阳性率差异无统计学意义;肉眼血尿、发热、血便等并发症发生率A组明显高于B组和C组(P<0.05)。结论直肠超声引导下经会阴前列腺24针穿刺法不但诊断正确率高,而且安全性好、并发症少,是一种理想的早期前列腺癌诊断方法。
Objective To evaluate the clinical value of different puncture patterns in the diagnosis of prostate cancer. Methods The clinical data of 475 patients undergoing prostate biopsy were retrospectively analyzed. Transrectal puncture group (group A) 110 cases, perineal puncture group (group B) 144 cases, perineal puncture group 24 cases (group C) 221 cases, the three groups in each of the prostate specific antigen (PSA) On the positive rate and the incidence of complications such as indicators, and further analysis of C group of patients with positive pin number distribution. Results The positive rate (34.2%) in group C was significantly higher than that in group A (10.8%) and group B (13.0%) with PSA <10.0μg / L; PSA10.0-60.0μg / L and PSA> 60.0μg / L patients, the positive rate of the three groups was no significant difference; the incidence of gross hematuria, fever, bloody stool and other complications in group A was significantly higher than those in group B and C (P <0.05). Conclusion Rectal ultrasound guided by the perineal prostate 24-pin puncture method not only high diagnostic accuracy, but also good safety, fewer complications, is an ideal early diagnosis of prostate cancer.