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目的研究在ICU患者多重耐药感染中应用替加环素的辅助治疗效果。方法对20例ICU多重耐药感染患者行替加环素辅助治疗,将患者的临床治疗效果、症状变化以及细菌清除指标进行记录统计,并与其行基础治疗的20例患者进行指标结果的统计比较。结果行基础治疗的患者其临床指标恢复时间以及清除率均低于行替加环素治疗的患者,两组数据对比呈现为P<0.05,表明统计学意义存在,其中两组的不良反应比较,呈现为P>0.05,表明无统计学意义。结论将替加环素辅助应用于ICU患者多重耐药菌感染病症的治疗中,具有显著的临床效果,能够对患者症状的改善起到帮助性作用,并良好的将细菌清除,这对于临床研究具有重要作用。
Objective To study the effect of adjuvant therapy with tigecycline in multi-drug resistant infections in ICU patients. Methods Twenty patients with multidrug-resistant ICU were treated with tigecycline adjuvant therapy. The clinical efficacy, symptoms and bacterial clearance of patients were recorded and statistically compared with those of the 20 patients who underwent basic treatment . Results The patients in the basic treatment group had lower recovery time and clearance rate than those treated with tigecycline. The data of the two groups showed P <0.05, indicating statistical significance. The adverse reactions of the two groups were compared, Present as P> 0.05, indicating no statistical significance. Conclusion The application of tigecycline in the treatment of multiple drug-resistant bacterial infections in ICU patients has significant clinical effect, which can help to improve the symptoms of patients and remove the bacteria well, which is of great value in clinical research Has an important role.