患孩女 ,1岁 6个月 ,以嗜睡伴烦躁不安、呕吐半天为主诉急诊我院。患孩自幼多病 ,易患上呼吸道感染 ,出生体重3.1kg,进食量较多 ,多尿 ,渐消瘦 ,生长发育缓慢 ,语言不清 ,至今不能独坐 ,虽经补钙及口服 Vit A+ D滴剂等治疗无明显效果。其父母健在 ,其姐患动脉导管未闭。体检 :T Children suffering from 1-year-old 6 months, to sleepiness with restlessness, vomiting for half a day mainly for emergency hospital. Early childhood sick child, susceptible to upper respiratory tract infection, birth weight 3.1kg, eating more, polyuria, weight loss, growth and development is slow, unclear language, so far can not sit alone, although by calcium and oral Vit A + D drops and other treatment no significant effect. His parents are alive, his sister suffering from patent ductus arteriosus. Physical examination: T.