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观察大蒜对甲基硝基亚硝基胍（ＭＮＮＧ）诱发大鼠腺胃胃癌及癌前病变影响，ＭＮＮＧ组、预防组、治疗组分别诱发腺瘤１５例、９例、３例，不典型腺癌１３例、５例、６例，息肉２３例、１６例、１１例，不典型息肉２１例、１７例、７例，微囊２４例、２１例、１７例，不典型微囊１６例、８例、３例，重度不典型增生２３例、１３例、９例，粘膜肉瘤２３例、６例、５例，浸润癌１９例、３例、４例，加用大蒜的预防与治疗组均有显著性差异，表明大蒜对ＭＮＮＧ诱发大鼠腺胃癌及癌前病变有显著的抑制和逆转作用。
Observed the effects of MNNG on gastric adenocarcinoma and precancerous lesions in rats. MNNG group, prevention group and treatment group induced adenoma in 15 cases, 9 cases and 3 cases, respectively. There were 13 cases, 5 cases, and 6 cases of cancer, 23 cases of polyps, 16 cases and 11 cases of polyps, 21 cases of atypical polyps, 17 cases, 7 cases, 24 cases of microcapsules, 21 cases, 17 cases, 16 cases of atypical microcapsules, In 8 and 3 cases, severe dysplasia occurred in 23 cases, 13 cases, and 9 cases. Mucosal sarcoma was found in 23 cases, 6 cases, and 5 cases. Invasive carcinoma was 19 cases, 3 cases, and 4 cases. Prevention and treatment with garlic There was a significant difference, indicating that garlic has a significant inhibition and reversal effect on MNNG-induced gastric adenocarcinoma and precancerous lesions in rats.