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据美国疾病控制中心估计,美国每年有20万乙型肝炎病毒(HBV)感染的新病例。大约25％的病人有明显症状,约1万人需要住院,其中1～2％的住院病人死于疾病的急性期。仅美国就有80万HBV携带者,每年在新感染的人中还有5～10％(每年1～2万)变成慢性携带者,其中一些人将发展为肝硬变或肝细胞癌。HBV感染是非酒精中毒性肝硬变的主要原因。慢性乙型肝炎患者中每年因肝硬变死亡者约为4,000人。被认为是HBV感染率低地
According to the U.S. Centers for Disease Control and Prevention, there are 200,000 new cases of hepatitis B virus (HBV) infection each year in the United States. Approximately 25% of patients have significant symptoms and about 10,000 need hospitalization, with 1% to 2% of inpatients dying from the acute phase of the disease. In the United States alone, there are 800,000 HBV carriers, and between 5 and 10% of new infections (between 1 and 20,000 per year) become chronic carriers each year, some of whom develop cirrhosis or hepatocellular carcinoma. HBV infection is the leading cause of non-alcoholic cirrhosis. About 4,000 people die of cirrhosis each year in patients with chronic hepatitis B. It is considered as a low HBV infection rate