本文报告2例类固醇敏感性系膜IgA肾病。例1:22岁,男性,治疗前肾活检,光镜示系膜基质和细胞中度增生;免疫萤光镜示中度Iga系膜沉积,无纤维蛋白、C_3、IgG和IgM沉积;电镜示系膜区中度电子致密物沉积,应用强的松龙1mg/kg/d,治疗两周,减量时复发,第3次复发时给予环磷酰胺1.5mg/kg。治疗结束后两年再次做肾活检,光镜示正常;免疫萤光镜示部分肾小球系膜区轻度IgA沉积,无 This article reports 2 steroid-sensitive mesangial IgA nephropathy. Example 1: 22-year-old man with pre-treatment renal biopsy, light microscope showing moderate proliferation of mesangial matrix and cells; Immunofluorescence with moderate Iga mesangial deposition, no fibrin, C_3, IgG, and IgM deposition; Medium electron density of mesangial deposition, the application of prednisolone 1mg / kg / d, for two weeks, relapse reduction, the third relapse given cyclophosphamide 1.5mg / kg. Renal biopsy was performed again two years after the end of treatment, and the light was normal. Immunofluorescence showed mild IgA deposition in the glomerular mesangial area, and no