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为了探讨Krukenberg瘤的临床特点,提高诊治水平,回顾性分析25例误诊为原发性卵巢癌的Krukenberg瘤患者的临床资料。25例患者年龄24～71岁,平均年龄37.4岁。临床表现为下腹部疼痛,腹胀、下腹部肿块,体检发现卵巢肿块等。15例病例术中病理冷冻切片确诊为Krukenberg瘤。25例都行子宫双侧附件切除术,术中15例探查发现原发病灶,行原发病灶切除术,其余10例术后2～6个月内再次行手术治疗,其中5例因广泛转移而失去切除机会。术后随访6个月～5年,总体平均生存期为1.2年。Krukenberg瘤在临床上很难与原发性卵巢癌作鉴别,提高认识、详细询问病史、术中探查胃肠道及病理冷冻切片是减少误诊的关键。
In order to explore the clinical features of Krukenberg’s tumor and improve the diagnosis and treatment, clinical data of 25 patients with Krukenberg’s tumor misdiagnosed as primary ovarian cancer were retrospectively analyzed. 25 patients aged 24 to 71 years, with an average age of 37.4 years. Clinical manifestations of lower abdominal pain, abdominal distension, abdominal mass, physical examination found ovarian mass. 15 cases of pathological frozen sections confirmed Krukenberg tumor. Twenty-five patients underwent bilateral bilateral hysterectomy. Among them, 15 cases were found to have primary lesion by primary exploration and primary excision. The remaining 10 cases were treated surgically within 2 to 6 months after surgery. Among them, Lose the chance of removal. Follow-up 6 months to 5 years after surgery, the overall average survival was 1.2 years. Krukenberg tumor in clinical difficult to identify with primary ovarian cancer, raise awareness, detailed history, intraoperative exploration of gastrointestinal and pathological frozen section is the key to reduce misdiagnosis.