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有人认为血小板可能与偏头痛的发病机理有关,但偏头痛是否主要为血小板功能异常所致尚未获证实。许多治疗偏头痛的药物对血小板凝聚有影响。由于阿斯匹林抑制血小板功能的剂量要比其镇痛剂量低得多,故有可能研究该药这两种作用之间的关系。为此本文作者对27例患者进行了随机双盲对照研究。本组患者为典型或普通型偏头痛,发作频率至少每月1次,无其它严重疾病,不服用其它干扰血小板功能的药物。在6个月中进行阿斯匹林160mg/日、安慰剂随机双盲交替研究。每3个月为一个阶
Some people think that platelets may be related to the pathogenesis of migraine, but whether migraine is mainly due to abnormal platelet function has not been confirmed. Many medications that treat migraine have an effect on platelet aggregation. Because aspirin suppresses platelet function at a much lower dose than analgesic, it is possible to study the relationship between the two effects of the drug. To this end the authors of the 27 patients were randomized double-blind controlled study. This group of patients with typical or common type of migraine, seizure frequency at least once a month, no other serious diseases, do not take other drugs that interfere with platelet function. Six-month aspirin 160 mg / day, placebo randomized double-blind alternation study. Every 3 months as a step