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目的 :研究急性脑梗死 (ACI)血压变化规律及其与神经功能损伤的关系。方法 :通过动态血压监护 ,探讨 ACI患者血压变化规律、及其对神经功能损伤的影响。结果 :(1 ) ACI发病后血压先迅速增高 ,维持 3天左右后自发回落 ,至第 7日基本稳定。(2 )约 38%的 ACI患者血压回落明显 ,其中 56%伴发神经功能损伤进展。(3)发病年龄高、初始神经功能损伤严重和大剂量应用甘露醇、硫酸镁、硝酸甘油与血压降低有关。结论 :ACI患者血压呈先增高再回落的自发趋势 ,血压过度降低可造成神经功能损伤进展
Objective: To study the changes of blood pressure in acute cerebral infarction (ACI) and its relationship with neurological impairment. Methods: By ambulatory blood pressure monitoring, we investigated the changes of blood pressure in ACI patients and their effects on neurological impairment. Results: (1) After the onset of ACI, the blood pressure increased rapidly first and then spontaneously dropped after about 3 days, and was basically stable on the 7th day. (2) About 38% of patients with ACI had a significant drop in blood pressure, of which 56% had progressive neurological impairment. (3) age of onset, severe initial neurological damage and high doses of mannitol, magnesium sulfate, nitroglycerin and decreased blood pressure. Conclusion: The blood pressure of ACI patients first increases and then decreases spontaneously. The excessive decrease of blood pressure can cause the damage of nerve function