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目的与可折叠单焦点AKREOS ADAPT人工晶状体(IOL)比较,通过检测视力和药物诱导下前房深度 (ACD)、瞳孔直径(PD)的变化,评价1CU可调节IOL(AIOL)植入术后的调节效果。设计非随机化临床试验。研究对象 44 例(53眼)老年性白内障患者分为两组:1CU AIOL组20例(23眼),对照组24例(30眼)。方法全部患者行白内障超声乳化吸除联合IOL植入术,术后3个月观察远、近视力,使用OCULUS Pentacam三维前房分析仪测量2％匹罗卡品眼液诱导前后的 ACD和PD值。主要指标非矫正远近视力、最佳矫正远视力、远视力矫正下的近视力,药物诱导前后的ACD、PD差值和ACD差值与远视力矫正下的近视力的相关关系。结果术后3个月1CU AIOL组与对照组矫正或非矫正远、近视力均无统计学差异。药物诱导下的ACD变化值1CU AIOL组与对照组分别为(0．07+0．02)mm、(0．05±0．03)mm(P=0．04);PD变化值1CU AIOL组与对照组分别为(0．32±0．19)mm、(0．57±0．30)mm(P=0．00)。药物诱导下的ACD变化值与远视力矫正下的近视力无显著相关(r= 0．1,P=0．5)。结论本研究显示1CU AIOL在眼内仅有O．07mm移动度,虽优于对照组但仍不足以产生明显的调节。需要以科学的态度采用客观的检测方法(如OCULUS Pentacam三维前房分析仪)评估AIOL的调节效果。未来的研究应考虑包括PD在内的鉴别假性调节的因素。
Objective To evaluate the changes of anterior chamber depth (ACD) and pupillary diameter (PD) after visual acuity and drug-induced foldable single-focus AKREOS ADAPT intraocular lens (IOL) Adjust the effect. Design non-randomized clinical trials. Forty-four patients (53 eyes) with senile cataract were divided into two groups: 20 cases (23 eyes) in the 1CU AIOL group and 24 eyes (30 eyes) in the control group. Methods All patients underwent phacoemulsification combined with IOL implantation. Far and near visual acuity was observed 3 months after operation. The ACD and PD values of 2% pilocarpine eye drops before and after induction were measured by OCULUS Pentacam three-dimensional anterior chamber analyzer . The main indicators of uncorrected distance vision, best corrected distance vision, distance vision correction of near vision, before and after drug induced ACD, PD difference and ACD difference with far vision correction of near vision correlation. Results There was no significant difference in corrected or uncorrected distance and near vision between 1CU AIOL group and control group at 3 months after operation. The changes of ACD induced by drugs were (0.07 ± 0.02) mm and (0.05 ± 0.03) mm (P = 0.04) (0.32 ± 0.19) mm and (0.57 ± 0.30) mm respectively compared with the control group (P = 0.00). There was no significant correlation between the changes of ACD induced by drugs and the near visual acuity under distance vision correction (r = 0.1, P = 0.5). Conclusion This study shows that 1CU AIOL is only O in the eye. 07mm mobility, although better than the control group but still not enough to produce significant adjustment. The need for a scientific attitude using objective detection methods (such as OCULUS Pentacam three-dimensional anterior chamber analyzer) to assess the effect of AIOL regulation. Future studies should consider factors that include the identification of pseudoregulation, including PD.