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In recent years,cancer has been one of the leading causes of death in the world.Much effort has been devoted to developing cancer treatments.Photodynamic therapy(PDT) is a noninvasive therapeutic modality by combining the light of a specific wavelength,a photosensitizer(PS) and oxygen,which has been widely applied for the treatment of cancers.However,the application of PDT in clinic is greatly limited due to lack of tumor selectivity and often causing skin photosensitivity.The use of organic nanoparticles(NPs) as an advanced technology in the field of PDT shows a great promise to overcome these shortcomings.Therefore,in this review,we summarize several functional organic NPs as PS carriers that have been developed to enhance the efficacy of PDT against cancers.
In recent years, cancer has been one of the leading causes of death in the world. Much effort has been devoted to developing cancer treatments. Photodynamic therapy (PDT) is a noninvasive therapeutic modality by combining the light of a specific wavelength, a photosensitizer ( PS) and oxygen, which has been widely applied for the treatment of cancers. Host, the application of PDT in clinic is greatly limited due to lack of tumor selectivity and often causing skin photosensitivity. The use of organic nanoparticles (NPs) as an advanced technology in the field of PDT shows a great promise to overcome these shortcomings.Therefore, in this review, we summarize several functional organic NPs as PS carriers that have been developed to enhance the efficacy of PDT against cancers.