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突变型ｐ５３蛋白在肝细胞性肝癌中的表达及临床意义温增庆吴孟超陈汉钱光相许多研究表明，癌的发生与癌基因激活和抑癌基因失活有关，抑癌基因中ｐ５３基因研究比较清楚。ｐ５３基因失活方式主要是突变，突变后的ｐ５３基因则失去了抑癌功能，现其产物ｐ５３蛋白可用免疫...
Expression of mutant p53 protein in hepatocellular carcinoma and its clinical significance Wen Zengqing Wu Mengchao Chen Han Qian Guangxiang Many studies have shown that the occurrence of cancer is related to the activation of oncogenes and the inactivation of tumor suppressor genes. The study of p53 gene in tumor suppressor genes is relatively clear. . The inactivation mode of p53 gene is mainly mutation, the p53 gene after mutation has lost the function of tumor suppressor, and the p53 protein of the product is available for immunity...