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3.激素 3.1 糖皮质激素在过去几年中,虽经大量研究,发展了一系列结构不同的衍生物,但并未获得全身作用或局部作用有显著改进的糖皮质激素。企图使糖皮质激素的解热作用、抗变态反应作用或免疫抑制作用成倍增强或使其与代谢作用和下丘脑-垂体-肾上腺皮质功能分离的努力至今仍未成功。关于Deflazacort(32)是否具有代谢作用较小的优点,最近曾开展讨论。在外用糖皮质激素方面,为获得完全保持原有疗效,但
3. Hormone 3.1 Glucocorticoids In the past few years, despite extensive research, a series of derivatives of different structures have been developed, but no systemic or topical glucocorticoids have been obtained. Attempts to decongest glucocorticoids, anti-allergic or immunosuppressive effects, or their efforts to separate the metabolic and hypothalamic-pituitary-adrenocortical functions have not been successful. Discussions have recently been held on whether Deflazacort (32) has the merit of being less metabolizable. In the external glucocorticoid, in order to maintain the original effect completely, but