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为探讨一氧化氮(NO)与分娩发动的关系,我们采用NO间接比色法,测定正常妊娠妇女150例血清NO含量,其中早期、中期、晚期妊娠、分娩期及产后期各30例,对照组30例,为非孕育龄妇女。结果显示,早期、中期、晚期妊娠和分娩期NO含量明显高于非孕育龄妇女(P<0.01)。产后妇女NO含量与非孕妇女无显著差别(P>0.05)。中期妊娠妇女NO含量明显高于早期妊娠及晚期妊娠的妇女(P均<005)。产后NO含量明显低于晚期妊娠。(P<0.05)。我们认为,孕期NO含量变化在维持正常妊娠生理及分娩发动中起重要作用。
To explore the relationship between nitric oxide (NO) and labor onset, we used NO indirect colorimetric method to determine serum NO level in 150 normal pregnant women, including 30 cases of early, middle, late pregnancy, childbirth and the postpartum period, Group of 30 cases, non-gestational age women. The results showed that the content of NO in early, middle and late pregnancy and childbirth was significantly higher than that in non-pregnant women (P <0.01). Postnatal women NO content and non-pregnant women no significant difference (P> 0.05). The NO level in mid-term pregnant women was significantly higher than that in early pregnancy and late pregnancy (all P <005). Postpartum NO content was significantly lower than that of late pregnancy. (P <0.05). We believe that changes in NO during pregnancy play an important role in maintaining normal pregnancy physiology and childbirth.