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甲(进修医生):肾病综合征(nephrotic syndrome,NS)的诊断标准,目前临床上很不一致,您能谈谈您的观点吗? 教师:在典型的病例,病人常有大量蛋白尿,低白蛋白血症、高脂血症和水肿。但后3者常是大量蛋白尿的直接或间接的后果。低白蛋白血症与尿内大量丢失蛋白,肾分解代谢增加和肝综合白蛋白的能力不足有关;水肿是由于低白蛋白血症导致血胶体渗透压降低,血管内的水向细胞间液转移,由于有效血容
A: The diagnostic criteria of nephrotic syndrome (NS) are clinically very different at present. Can you talk about your opinion? Teacher: In a typical case, patients often have a lot of proteinuria, low white Proteins, hyperlipidemia and edema. However, the latter three are often the direct or indirect consequences of large amounts of proteinuria. Hypoalbuminemia is associated with a large amount of lost protein in the urine, an increased renal catabolism, and an insufficient capacity of synthetic liver albumin; the edema is due to hypoalbuminemia leading to a decrease in the blood colloid osmotic pressure, intravascular water transfer to the interstitial fluid , Due to effective blood volume