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应用免疫组织化学BSA法检测32例卵巢克鲁根勃瘤、20例卵巢癌中P53蛋白、雌激素受体（ER）、孕激素受体（PR），其阳性表达率克鲁根勃瘤分别10.9％（13／32）、21.9％（7／32）、21．9％（7／32），卵巢癌依次为45％（9／20）、65％（13／20）、50％（10／20）。结果表明P53在两者中阳性表达率无显著相关性，ER、PR在高分化卵巢癌中阳性表达率明显高于克鲁根勃瘤及低分化卵巢癌（P＜0．001）。在卵巢癌中ER、PR阳性表达率与组织学分化程度正相关（P＜0．05）与预后负相关（P＜0．01）。
Immunohistochemical BSA was used to detect the expression of P53 protein, estrogen receptor (ER) and progesterone receptor (PR) in 32 cases of Crohn’s tumor of ovary and 20 cases of ovarian cancer, respectively. The positive rate of Creutzfeldt- (9.9%), 21.9% (7/32) and 21.9% (7/32) respectively in 10.9% (13/32), 45% (9/20), 65% / 20). The positive rates of P53 expression in well-differentiated ovarian cancer were significantly higher than those in Crohn’s tumor and poorly differentiated ovarian cancer (P <0.001). The positive rate of ER and PR in ovarian cancer was positively correlated with histological differentiation (P <0.05) and negatively correlated with prognosis (P <0.01).