穿心莲全草在印度传统医药中用于解热、滋补、健胃、驱虫和保肝等。作者研究了该植物提取物的精神药理学活性。该植物粉碎后用甲醇提取,提取物减压蒸干得半固形物,将其溶于生理盐水供实验用。各种试验均将大或小鼠分为4组,分别注射100、200和300 mg/kg的提取物及生理盐水(对照组)。另设地西泮(10mg/kg)阳性对照组。给药30min后,腹腔注射戊巴比妥40mg/kg,研究该提取物对睡眠时间的影 Andrographis paniculata is used for antipyretic, nourishing, stomachic, anthelmintic and hepatoprotective in traditional Indian medicine. The authors studied the psychopharmacological activity of the plant extract. The plant was crushed and then extracted with methanol. The extract was evaporated to dryness under reduced pressure to obtain a semisolid, which was dissolved in physiological saline for experimental use. In each experiment, large or small mice were divided into 4 groups and injected with 100, 200, and 300 mg/kg of the extract and physiological saline (control group), respectively. Separately, Xiqiao (10mg/kg) positive control group was set up. After 30 minutes of administration, pentobarbital 40 mg/kg was intraperitoneally injected to study the effects of the extract on sleeping time.