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目的：探讨急性心肌梗死（AMI）患者肺泡动脉血氧分区差及肺功能与心功能受损程度的相关性。方法：对35例AMI患者据心功能（Killip）分级不同进行分组，分别行血气分析和肺功能各指标（FEV1.0、FVC、V50及V25）监测，并计算肺泡动脉血氢分压差（A－aDO2）。比较各组间上述指标的差别。结果：AMI当日即有动脉血氧分压（PaO2）的下降，A-aDO2。的增大，并随病情改善而渐趋恢复。PaO2及肺功能各指标在各组间差别具有统计学意义（P＜0．05）。不同的梗塞部位A－aDO2亦不同，差别具有统计学意义（P＜0．05）。结论：在AMI患者测定PaO2、A－aDO2及肺功能指标对评价心功能状况具有重大意义，值得在临床工作中推广应用。
Objective: To investigate the relationship between pulmonary arterial oxygenation and pulmonary function and cardiac dysfunction in patients with acute myocardial infarction (AMI). Methods: Thirty-five patients with AMI were divided into different groups according to their Killip grades. Blood gas analysis and pulmonary function indexes (FEV1.0, FVC, V50 and V25) were respectively monitored to calculate the difference of partial pressure of hydrogen in alveolar artery A-aDO2). Compare the differences between the above indicators. Results: The arterial partial pressure of oxygen (PaO2) decreased on the day of AMI, A-aDO2. Of the increase, and with the improvement of the condition gradually recovered. PaO2 and pulmonary function indicators in each group difference was statistically significant (P <0.05). Different infarct size A-aDO2 also different, the difference was statistically significant (P <0.05). Conclusion: The determination of PaO2, A-aDO2 and pulmonary function parameters in patients with AMI is of great significance for the evaluation of cardiac function, which is worth popularizing in clinical practice.