论文部分内容阅读
羟基脲(H_2N·CO·NHOH, Hydroxyurea, Hydrea,以下简称HU)是在1869年合成的简单化合物,近十年发现它具有抗癌作用,能特异性地抑制脱氧核糖核酸的合成,目前已在临床上应用。1974年3月在广州举行了该药的技术鉴定会议,准备投入生产。抗癌作用及其原理一、动物抗瘤试验:HU的抗瘤作用在1963年才开始被证实。Stearns等用HU于白血病L1210小
Hydroxyurea (H 2 N · CO · NHOH, Hydroxyurea, Hydrea, hereinafter referred to as HU) is a simple compound synthesized in 1869. It has been found that it has anti-cancer effect in the recent ten years and can specifically inhibit the synthesis of DNA. Clinical application. March 1974 in Guangzhou held a technical appraisal meeting of the drug, ready for production. Anti-cancer effect and its principle First, animal anti-tumor test: HU anti-tumor effect was only confirmed in 1963. Stearns et al used HU for leukemia L1210