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以丙二酸和异丁醛为起始原料 ,通过 Knoevenagel缩合 ,再经异构化和内酯化反应合成了γ-甲基 - 1 ,4-戊内酯 ,总收率 53%
Using malonic acid and isobutyraldehyde as starting materials, γ-methyl-1, 4-valerolactone was synthesized by Knoevenagel condensation and isomerization and lactonization. The total yield was 53%