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研究正常、妊娠及慢性炎症三种状态下输卵管粘膜凝集素受体表达及其相互关系。应用免疫组织化学 ABC方法 ,以六种生物素化的凝集素为探针 ,对以上三种状态下的输卵管粘膜凝集素受体进行标记。结果表明 PNA.U EA - 1.SJA的表达在分泌期比增生期为强 ;妊娠时输卵管壶腹部粘膜 DBA、 PNA、 SJA表达比分泌期为强 ,而 UEA- 1表达比分泌期减弱 ;慢性输卵管炎粘膜凝集素受体的表达与输卵管妊娠时接近或相同。提示 :月经周期中输卵管粘膜凝集素受体的表达受雌激素及孕激素的调节 ;输卵管妊娠时的表达除受雌孕激素的影响外 ,还可能与着床时胚泡的局部作用有关 ;慢性输卵管炎易致输卵管妊娠的因素之一 ,可能与输卵管粘膜凝集素受体的改变有关
To study the expression of tubal mucosal lectin receptor and its relationship in three states of normal, pregnancy and chronic inflammation. Using immunohistochemical ABC method, six kinds of biotinylated lectins were used as probes to label the tubal mucosal lectin receptors in the above three states. The results showed that the expression of PNA.U EA - 1.SJA was stronger in the secretory phase than that in the proliferative phase. The expression of DBA, PNA and SJA in the ampulla of the oviduct during pregnancy was stronger than that during the secretory phase, while the expression of UEA - 1 was weaker than that during the secretory phase. Salpingitis mucosal lectin receptor expression and tubal pregnancy close or the same. Tip: the expression of tubal lectin receptor in the menstrual cycle by estrogen and progesterone regulation; tubal pregnancy in addition to the expression of estrogen and progesterone, but also may be related to the local role of blastocyst implantation; chronic Salpingitis prone to tubal pregnancy, one of the factors that may be related to tubal lectin receptor changes