胰岛素依赖型糖尿病最常见的神经血管性并发症的发病率随年龄增长而升高。目前认为糖尿病的神经性病变是周围神经系统中最常见的一种病理变化过程。慢性糖尿病病人最后几乎有一半病人可累及此病。其临床表现最常见是肢体末端对称性感觉障碍,包括感觉迟纯和感觉异常,还可有向心性痛觉传导柬功能障碍。此时,无论机体整体血糖水平控制如何,均可造成下肢和足部严重的功能性损害及顽固性疼痛。对于此种疼痛症状的控制已成为临床治疗上难题。应用多种止痛剂、抗抑郁药、抗惊厥药及 The incidence of insulin-dependent diabetes mellitus, the most common neurovascular complication, increases with age. Currently considered diabetic neuropathy is the most common peripheral nervous system, a pathological process. In the end almost half of patients with chronic diabetes can be affected by the disease. The most common clinical manifestations of limb symmetry of the end of sensory disorders, including the feeling of pure and sensory abnormalities, but also can have cardiac pain conduction cardiopulmonary dysfunction. At this point, no matter how the body’s overall blood glucose control, can cause severe functional impairment of the lower extremities and feet and intractable pain. Control of such painful symptoms has become a clinical problem. Use a variety of analgesics, antidepressants, anticonvulsants and