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[目的]了解Kimura病的临床病理特征。[方法]回顾分析8例Kimura病患者的临床资料。[结果]1例患者以腹胀、腹泻、双下肢浮肿起病,伴下腹部散在红色丘疹及双侧耳后淋巴结、肠系膜淋巴结肿大。7例患者以颈部肿块就诊。8例均行肿块切除、皮质激素或细胞毒药物治疗。[结论]外周血嗜酸性粒细胞和血清IgE升高对该病的诊断具有重要意义。皮质激素应作为Kimura病的首选治疗方法。
[Objective] To understand the clinicopathological features of Kimura disease. [Methods] The clinical data of 8 patients with Kimura disease were retrospectively analyzed. [Results] One patient had abdominal distension, diarrhea and edema of both lower extremities. The lower abdomen was scattered with red papules and bilateral posterior ear lymph nodes. The mesenteric lymph nodes were swollen. Seven patients were treated with a neck mass. All patients underwent tumor resection, corticosteroids or cytotoxic drugs. [Conclusion] The increase of peripheral blood eosinophil and serum IgE is of great significance for the diagnosis of the disease. Corticosteroids should be the treatment of choice for Kimura disease.