【摘 要】
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目的对鼾症老年人中睡眠呼吸暂停低通气综合征(SAHS)与部分心血管异常改变的相关性及经鼻持续气道正压通气(nCPAP)对SAHS的有关疗效作一观察.方法采用多导睡眠仪将67例60岁以
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目的对鼾症老年人中睡眠呼吸暂停低通气综合征(SAHS)与部分心血管异常改变的相关性及经鼻持续气道正压通气(nCPAP)对SAHS的有关疗效作一观察.方法采用多导睡眠仪将67例60岁以上老年鼾症者分为SAHS组和非SAHS组,通过动态心电图及血压检测仪就两组血压昼夜节律、高血压、心率变异性、部分心律失常、冠心病心绞痛的状况作出比较.在SAHS组中将接受nCPAP治疗5-7天后有关心血管状况与治疗前加以比较.结果鼾症老人中SAHS的发病率较高(47.9%);在SAHS组中,高血压、血压昼夜节律消失、冠心病心绞痛时硝酸盐疗效不佳、睡眠期心率变异性降低、心律失常及脉氧饱和度(SpO2)降低的发生率均明显高于非SAHS组.经nCPAP治疗后睡眠期不仅鼾声消除、SpO2明显增高和呼吸暂停/低通气指数明显降低;而且心率变异性和血压昼夜节律恢复.结论本研究提示SAHS与老龄心血管疾病的发生和发展有密切的相关性,应用nCPAP不仅对SAHS有较满意的疗效,而且对改善患者的心血管病变也有重要作用.
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