自从1961年Novotny和Alvis发明用荧光素钠静脉注射作为对某些眼底病的研究方法以来,国外已大量应用于临床。目前它已成为眼科学重要的诊断和研究工具,是眼内疾病常规的检查方法之一。我国由于缺乏静脉注射用荧光素钠制剂,开展此项工作受到一定的限制。1972年南京军区总医院首先开展此项研究,此后各地不少医院相继应用于临床,其文献报道也日渐增多,现将这方面的概况作一综述。 Since 1961, Novotny and Alvis invented intravenous injection of sodium fluorescein as a research method for some fundus disease, a large number of clinical applications abroad. It has now become an important diagnostic and research tool for ophthalmology and is one of the routine tests for intraocular conditions. Our country due to the lack of intravenous sodium fluorescein preparations to carry out this work subject to certain restrictions. In 1972, Nanjing Military Region General Hospital first carried out this study. Since then, many hospitals in different places have been used in clinical practice one after another, and their reports in the literature have been increasing. Now, the overview of this field is reviewed.