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目的评估以铋剂为基础的三联疗法根治 Hp感染的疗效。方法将 67例 Hp阳性的活动性胃、十二指肠溃疡患者随机分为治疗组和对照组。治疗组给予一周奥美拉唑及丽珠胃三联 ,对照组给予奥美拉唑 ,一周后检查溃疡愈合情况及一月后 Hp根除率。结果消化性溃疡患者治疗一周后复查胃镜 ,溃疡总愈合率 :治疗组 94.4% (3 4/ 3 6) ,对照组为 87.1% (2 7/ 3 1) ,两组溃疡愈合率无显著性差异。停药一个月后 Hp根除率 :治疗组 10 0 % (3 6/ 3 6) ,对照组 12 .9% (4 / 3 1) ,治疗组 Hp根除率明显高于对照组 ,有显著性差异 (P<0 .0 1)。结论丽珠胃三联疗法对消化性溃疡治疗中短期疗效显著、用法简便、不良反应少、安全 ,治疗效果优于其它标准方案
Objective To evaluate the efficacy of bismuth-based triple therapy in the treatment of Hp infection. Methods 67 cases of Hp-positive active gastric and duodenal ulcer patients were randomly divided into treatment group and control group. Patients in the treatment group were treated with omeprazole and liguzhu for one week. Omeprazole was given to the control group. One week later, ulcer healing and one-month Hp eradication were examined. Results The patients with peptic ulcer were examined by gastroscope one week after operation. The total healing rate of ulcer was 94.4% (34/36) in the treatment group and 87.1% (27/31) in the control group. There was no significant difference in healing rate between the two groups . The eradication rate of Hp after a month’s withdrawal was 10 0% (36/36) in the treatment group and 12.9% (4/3 1) in the control group, and the Hp eradication rate in the treatment group was significantly higher than that in the control group (P <0. 01). Conclusion Livzon stomach triple therapy for peptic ulcer in the treatment of short-term significant effect, easy to use, less adverse reactions, safety, the treatment effect is superior to other standard programs