自1895年伦琴发现X-射线后,人们开始注意电离辐射的危害,以后进行了一些防护辐射损伤的化学药物的研究,已合成和试验了数以千计个化合物,其中有很多药物对接受致死性辐射试验的动物具有显著的防护作用。本文扼要介绍化学辐射防护剂,并提出化学结构与生物效应问的相互关系,以期有助于新抗辐射药物的设计。辐射损伤的特性 Since Roentgen discovered X-rays in 1895, people began to pay attention to the dangers of ionizing radiation. Later, some studies on chemical drugs that protected against radiation damage have been carried out. Thousands of compounds have been synthesized and tested, many of which are fatal to death Sex-radiation test animals have a significant protective effect. This article gives a brief introduction of chemopreventive agents and proposes the interrelationship between chemical structure and biological effects so as to contribute to the design of new anti-radiation drugs. Characteristics of radiation damage