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目的:评估白内障术后疏水性丙烯酸人工晶状体Sensar AR40e和硅胶人工晶状体的后囊膜混浊(PCO),并用能客观评估PCO的软件量化分析。方法:共选择98眼行标准的超声乳化白内障吸除术,人工晶状体囊袋内固定。所有眼随机植入Sensar AR40e或硅胶人工晶状体,但同一患者植入的人工晶状体必须不同。在第1～2a时后照法拍摄后囊膜图像,通过去除浦肯野反光、增强对比度、过滤后增强低密度的PCO等方法处理后用POCO软件分析对比。结果:术后1a疏水性丙烯酸人工晶状体PCO百分比为0.32±0.13,硅胶人工晶状体为0.39±0.17(P=0.37)。2a时疏水性丙烯酸人工晶状体PCO百分比为0.42±0.20,硅胶晶状体为0.34±0.18(P=0.50)。患者术后1,2a时疏水性丙烯酸人工晶状体PCO的严重级别分别是0.50±0.30和0.82±0.58,与硅胶人工晶状体的0.63±0.35和0.55±0.35相比,无统计学意义(P=0.52,P=0.69)。结论:POCO后囊膜混浊量化分析系统提供了客观而且可重复性强的量化PCO的方法,也是研究预防PCO技术的有力工具。
PURPOSE: To evaluate posterior capsular opacification (PCO) of hydrophobic acrylic intraocular lens (ARSC) and intraocular lens (IOL) after cataract surgery, and to quantify the PCO software objectively. Methods: A total of 98 eyes were selected phacoemulsification cataract surgery, intraocular lens capsular fixation. Sensar AR40e or silicone intraocular lens was implanted randomly in all eyes, but the intraocular lens implanted in the same patient must be different. The posterior capsule images were taken at 1 to 2 years after surgery, and the contrast was analyzed by POCO software after removing the Purkinje reflections, enhancing the contrast, and filtering to enhance the low density PCO. Results: The percentage of PCO hydrophobic hydrophobic intraocular lens (IOP) after surgery was 0.32 ± 0.13 and 0.39 ± 0.17 (P = 0.37) respectively. The PCO percentage of hydrophobic acrylic lens was 0.42 ± 0.20 and that of silica gel lens was 0.34 ± 0.18 (P = 0.50). The severity of PCO in patients with hydrophobic acrylic intraocular lens at 1 and 2 days after operation was 0.50 ± 0.30 and 0.82 ± 0.58, respectively, which was not statistically significant compared with 0.63 ± 0.35 and 0.55 ± 0.35 of intraocular lens (P = 0.52, P = 0.69). Conclusion: POCO posterior capsular opacification quantitative analysis system provides an objective and reproducible method for quantifying PCO, and is also a powerful tool for studying the prevention of PCO.