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近年来我们对36例小儿神经性尿频患儿分两组分别试用消炎痛和复方新诺明治疗,观察如下:即患儿反复出现尿频、尿急症状,1日约10余次,每次尿量不多,无尿痛及其它症状,同时尿常规检查正常,尿糖阴性.诊断为小儿神经性尿频.Ⅰ组患儿18例、男8例、女10例、3～5岁11例,6～8岁7例。病程最短14日,最长6个月.Ⅱ组患儿18例、男11例、女7例,1～3岁9例、4～7岁8例,8岁1例.病程最短7日,最长2个月。治疗方法.Ⅰ组采用消炎痛口服、每次每公斤体重0.5毫克,最大量不超过25毫克/次,每日3次口服。5天为一疗程,如不见效,3天后行第2疗程。Ⅱ组采用复方新诺明治疗,每日每公斤体重50毫克,分2次口服,7天为1疗程。如不见效,3天后行第2个疗程.结果:Ⅰ组18例病例中、9例服药1个疗程后症状消失为显效,8例服药2个疗程后症状消失为有效。1例无效。Ⅱ组18例病例中2例显效,6例有效、10例无效经统计学处理差别有高度显著性(P值<0.01)。
In recent years, 36 cases of children with neurogenic urinary frequency in children were treated with indomethacin and cotrimoxazole in two groups, the observation is as follows: recurrent children with frequent urination, urgency symptoms, on the 1st about 10 times, each urine No small amount of urine, no dysuria and other symptoms, while urinary routine examination was normal, negative urine. Diagnosis of pediatric neurogenic frequency .I group of 18 children, 8 males and 10 females, 3 to 5 years old in 11 cases, 6 to 8 years old in 7 cases. The shortest duration of 14 days, a maximum of 6 months.Early group of 18 children, 11 males and 7 females, 1 to 3 years old in 9 cases, 4 to 7 years old in 8 cases, 8 years old in 1. The shortest duration of 7 days, Up to 2 months. The treatment group Ⅰ with indomethacin orally, each 0.5 mg body weight per kilogram, the maximum does not exceed 25 mg / time, 3 times a day orally. 5 days for a course of treatment, if not effective, 3 days after the first two courses. Group Ⅱ was treated with cotrimoxazole 50 mg / kg body weight per day, 2 times orally, 7 days for a course of treatment. If not effective, 3 days after the first two courses.Results: Ⅰ group of 18 cases, 9 cases after taking a course of treatment symptoms disappear markedly effective, 8 cases of medication after 2 courses of symptoms disappear effectively. 1 case is invalid. Among the 18 cases in group Ⅱ, 2 cases were markedly effective, 6 cases were effective and 10 cases were ineffective. The difference was statistically significant (P <0.01).