女婴,18天。因轻咳2天伴唇周青紫6小时入院。第三胎第一产,足月顺产,出生体重3.5kg,入院前两天咳嗽,渐加重,嗜睡,纳少。入院当天突然面色青紫,呼吸急促,以新生儿肺炎收入院。体检:T35.5℃,神清,呼吸60次,鼻扇(+),唇周及鼻唇沟紫绀,心率160次,律齐,心音低钝,无杂音,二肺呼吸音粗,未闻及干、湿啰音。肝肋下2cm,四肢末端凉。入院后即给予吸氧,水青加氨苄青抗感染治疗。入院3小时后病情进一步加剧,气促明显,鼻扇、紫绀加重,出现三凹征,呼吸65次,心率180～ Baby girl, 18 days. Due to light cough 2 days with lip weeks bruising 6 hours admission. The third birth of the first birth, term full-term, birth weight 3.5kg, two days before admission, cough, gradually heavier, lethargy, satisfied less. Suddenly looking bruise on admission day, shortness of breath, neonatal pneumonia income hospital. Physical examination: T35.5 ℃, Shen Qing, breath 60 times, nasal fan (+), lip circumference and nasolabial folds cyanosis, heart rate 160 times, law Qi, low heart sound blunt, no noise, And dry, wet rales. Liver ribs 2cm, extremities cold end. Admitted to hospital oxygen, water plus ampicillin anti-infection treatment. 3 hours after admission, the condition further aggravated, obvious shortness of breath, nasal fan, cyanosis increased, there were three concave sign, breath 65 times, heart rate 180 ~