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本文应用ＡｇＮＯＲｓ染色技术对３５例宫颈良恶性病变中的细胞核内ＡｇＮＯＲｓ的数量、形态、大小及分布进行光镜观察与对比分析。结果表明：炎性增生组细胞核内Ａｇ－ＮＯＲｓ数量少于不典型增生组，ＡｇＮＯＲｓ颗粒均分布于中位，颗粒呈圆形、卵圆形。在宫颈鳞癌中Ⅱ级、Ⅲ级ＡｇＮＯＲｓ明显多于Ⅰ级，也多于良性病变（Ｐ＜０．０１），并随细胞恶性程度的增高分布于核周的ＡｇＮＯＲｓ增多（Ｐ＜０．０１），并出现不规则形。因此，ＡｇＮＯＲｓ的检测在宫颈良恶性病变及肿瘤分级中有一定的参考价值。
AgNORs staining technique was used to observe the number, shape, size and distribution of AgNORs in 35 cases of benign and malignant cervical lesions by light microscopy and comparative analysis. The results showed that the number of Ag-NORs in inflammatory cells was less than that in atypical hyperplasia group, and the particles of AgNORs were distributed in the center. The particles were round and oval. In cervical squamous cell carcinoma, AgNORs of grade Ⅱ and Ⅲ were significantly more than grade Ⅰ and more than benign lesion (P <0.01), and the number of AgNORs distributed in perinuclear area increased with the increase of cell malignancy (P <0.01) ), And irregular shape. Therefore, the detection of AgNORs in cervical benign and malignant lesions and tumor grade have a certain reference value.