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胃十二指肠的营养和功能活动,许多取决于内分泌系统的调节;溃疡病的发病机制,内分泌障碍有一定作用。作者研究十二指肠溃疡病患者血液垂体促性腺激素(黄体生成素、卵泡刺激素),性激素(睾酮、雌二醇、雌三醇和孕酮)、促胃液素和环腺苷酸(激素分泌和效用介质)的含量,在同一条件下采血,女性在卵泡期采血,用放射免疫法测定上述激素的含量,数据资料进行统计学处理。 检查加重期十二指肠溃疡病184例(基本组)年龄20～60岁,男141例(65%病程10年),女43例(62%病例1～5年),没有伴发病和内分泌疾病。对照组为健康人81例(男40,女41)。
Gastroduodenal nutrition and functional activity, many depend on the regulation of the endocrine system; ulcer disease pathogenesis, endocrine disorders have a role. The authors studied the changes of blood pituitary gonadotropin (LH, FSH), sex hormones (testosterone, estradiol, estriol and progesterone), gastrin and cAMP in patients with duodenal ulcer And the utility medium), blood was collected under the same conditions, and women took blood during follicular phase. The contents of the above hormones were determined by radioimmunoassay, and the data were statistically processed. 184 patients with aggravating duodenal ulcer (basic group) aged 20-60 years, 141 males (65% course of disease for 10 years), 43 females (62% of cases 1 to 5 years) without concomitant diseases and endocrine disease. The control group of 81 healthy subjects (male 40, female 41).