帕金森氏病(Parkinsons dis-ease)亦称震颤麻痹,又称纹状体多巴胺缺乏综合征,为锥体外系运动障碍最常见的疾病。首先由Parkinson氏(1917年)、Charcot氏(1967年)提出。该病是由皮层下基底神经节(纹状体和黑质)病变所引起,特征为运动功能障碍、情感性和随意性运动减慢和无力、肌张力增强、震颤、屈曲姿势和面具脸等。 Parkinson’s disease (Parkinsons dis-ease), also known as Parkinson’s paralysis, also known as striatal dopamine deficiency syndrome, is the most common disease of extrapyramidal movement disorders. First proposed by Parkinson’s (1917), Charcot’s (1967). The disease is caused by lesions of the subcortical basal ganglia (striatum and substantia nigra), characterized by motor dysfunction, slowing and weakness of affective and voluntary movements, increased muscle tone, tremor, flexion and mask faces, etc. .