支持盆底的肌肉、筋膜、神经纤维等组织发生病变,导致盆底支持结构薄弱,从而促使盆底功能障碍性疾病的发生。研究表明,雄激素及其受体对于支持盆底的组织,如肌肉、胶原、神经纤维有促进作用。提示雄激素及其受体在盆底功能障碍性疾病的发生、发展、治疗中可能存在一定的作用,为揭示盆底功能性障碍疾病的病因、防治方法提供理论依据。 Support the pelvic floor muscles, fascia, nerve fibers and other tissue lesions, leading to pelvic floor support structure is weak, so as to promote pelvic floor dysfunction disease. Studies have shown that androgen and its receptors support the pelvic floor tissue, such as muscle, collagen, nerve fibers have a promoting effect. These results suggest that androgen and its receptor may play a role in the occurrence, development and treatment of pelvic floor dysfunction diseases, and provide a theoretical basis for revealing the etiology and prevention and treatment of pelvic floor functional disorders.