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近年,随着肽类激素内分泌学研究的进展,人们发现,在生殖道中也存在一些肽类激素,如促肾上腺皮质激素(ACTH)、β-内啡肽(β-Endorphin)等。舒血管肠肽(Vasoactive intestinal peptide,简称VIP)是70年代初发现的一种胃肠道激素,并可能具有神经递质的作用。因其广泛分布于胃肠道中并调节胃肠道的活动,同时又具有舒血管作用,因而被称为舒血管肠肽。近年的实验证明,在多种动物的雌性生殖道中也存在VIP能神经纤维,外源性VIP能使子宫平滑肌舒张。这提示,VIP有可能在子宫平滑肌收缩活动的局部调控中具有某
In recent years, with the progress of research on endocrinology of peptide hormones, some peptide hormones such as adrenocorticotropic hormone (ACTH), β-endorphin and the like have also been found in the genital tract. Vasoactive intestinal peptide (VIP) is a gastrointestinal hormone found in the early 1970s and may have the function of neurotransmitter. Because of its widespread distribution in the gastrointestinal tract and regulate the activity of the gastrointestinal tract, but also has a vasodilator effect, which is called vasoactive intestinal peptide. In recent years, experiments show that in a variety of animal females there are also VIP nerve fibers, exogenous VIP can make uterine smooth muscle relaxation. This suggests that VIP may have some in local regulation of uterine smooth muscle contractile activity