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目的探讨泌尿生殖道解脲脲原体(Uu)和人型支原体(Mh)感染情况及对10种抗菌药物的体外敏感性。方法采用支原体鉴定药敏检测试剂盒进行临床检测,并对结果进行统计分析。结果950例疑似泌尿生殖道感染患者检出支原体阳性493例,感染率51.9%。其中单独Uu阳性356例(37.5%),Uu+Mh阳性105例(11.1%),单独Mh阳性32例(3.4%)。男性患Uu感染率22.6%,女性患者Uu感染率44.5%,两者差异有统计学意义(P<0.05)。药敏结果表明交沙霉素、美满霉素、强力霉素的敏感度明显高于其他抗菌药物。结论泌尿生殖道支原体感染主要是Uu,其次为Uu+Mh合并感染;交沙霉素、美满霉素、强力霉素可作为目前泌尿生殖道感染支原体的经验性用药物。
Objective To investigate the genitourinary Uu and Mh infection and the sensitivity to 10 antimicrobial agents in vitro. Methods Mycoplasma identification drug sensitivity test kit for clinical testing, and the results were statistically analyzed. Results A total of 493 mycoplasma positive cases were detected in 950 cases of suspected genitourinary tract infection, the infection rate was 51.9%. Among them, 356 (37.5%) were positive for Uu alone, 105 (11.1%) were positive for Uu + Mh and 32 (3.4%) were positive for Mh alone. Uu infection rate was 22.6% in men and 44.5% in female patients, the difference was statistically significant (P <0.05). Susceptibility results show that josamycin, minocycline, doxycycline sensitivity was significantly higher than other antibacterials. Conclusions Mycoplasma genital tract infection is mainly Uu, followed by Uu + Mh infection; josamycin, minocycline and doxycycline can be used as empirical drugs for genitourinary tract infection of mycoplasma.