系统性红斑狼疮(SLE)累及多个系统,如首发表现或主要表现较为特殊,就容易误诊。本文报道2例于后。病例报告例1:女,41岁。因心悸1年半,心悸加重伴气短8个月,全身浮肿2个月,体查心尖区闻舒张期隆隆样杂音而诊为“风湿性心脏病二尖瓣狭窄”于1982 Systemic lupus erythematosus (SLE) involves multiple systems, such as the first performance or the main performance is more special, it is easy to misdiagnosis. This article reports 2 cases after. Case Report Example 1: Female, 41 years old. 1 year and a half due to heart palpitations, palpitations increased with shortness of breath for 8 months, systemic edema 2 months, physical examination of apex diastolic rumbling like noise and diagnosed as “rheumatic mitral stenosis” in 1982