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目的：吸烟是肺癌的重要的病因，本文探讨与烟草中多环芳烃类致癌物活化和解毒密切相关的代谢酶：ＣＹＰ１Ａ１和ＧＳＴＭ１的遗传多态性与肺癌易感性的关系。方法：应用病例对照设计，采集江苏省被检者抗凝外周血，保存于－７６℃低温冰箱中。按微量法提取ＤＮＡ，应用等位基?
OBJECTIVE: Smoking is an important cause of lung cancer. This paper discusses the relationship between the genetic polymorphisms of CYP1A1 and GSTM1 and the susceptibility to lung cancer, which are closely related to the activation and detoxification of the polycyclic aromatic hydrocarbons in tobacco. METHODS: Case-control design was used to collect anticoagulated peripheral blood from subjects in Jiangsu Province and stored in a low-temperature refrigerator at -76°C. According to the trace method to extract DNA, the application of allyl?